Effects of iron deficiency on neonatal behavior at different stages of pregnancy

This prospective study involved 216 pregnant Spanish mothers aged 18 to 43, and were followed from week 13 of gestation to childbirth. They were all supplemented with iron from week 15 (mean dose 48.8mg/d). A clinical follow-up including blood collection occurred three times during pregnancy until childbirth. The first blood collection was taken before iron supplementation whilst the other two occurred after supplementation (24-27 weeks, and 33-34 weeks of gestation). Neonatal behavior was assessed using the Neonatal Behavior Assessment Scale (NBAS). Through this method, the general autonomous response, motor performance and self-regulation abilities of the neonate could be measured amongst other parameters. Iron intake, especially in the third trimester was associated to NBAS scores.

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Reference
Hernandez-Martinez, C., et al., Effects of iron deficiency on neonatal behavior at different stages of pregnancy. Early Hum Dev, 2011. 87(3): p. 165-9.

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